TY  - BOOK
AU  - Aulton, Michael E.
TI  - Aulton's Pharmaceutics: The design and manufacture of medicines 
SN  - 9780443101083
AV  - RS200 .A95 2007
PY  - 2007///
CY  - Edinburgh
PB  - Churchill Livingstone
KW  - Drugs
KW  - Dosage forms
KW  - Design
KW  - Dosage Forms
KW  - Biopharmaceutics
KW  - Drug Design
N1  - Includes bibliographical references and index; What is 'pharmaceutics'? Design of dosage forms PART ONE: SCIENTIFIC PRINCIPLES OF DOSAGE FORM DESIGN *Dissolution and solubility *Properties of solutions *Rheology *Surface and interfacial phenomena *Disperse systems *Kinetics of product stability PART TWO: PARTICLE SCIENCE AND POWDER TECHNOLOGY *Solid-state properties *Particle size analysis *Particle size reduction *Particle size separation *Mixing *Powder flow. PART THREE: PHARMACEUTICAL MICROBIOLOGY AND STERILIZATION *Fundamentals of microbiology *Pharmaceutical applications of microbiological techniques *Action of physical and chemical agents on microorganisms *Principles of sterilization *Sterilization in practice PART FOUR: BIOPHARMACEUTICAL PRINCIPLES OF DRUG DELIVERY *Introduction to biopharmaceutics *Gastrointestinal tract - physiology and drug absorption *Bioavailability - physicochemical and dosage form factors *Assessment of biopharmaceutical properties *Dosage regimens PART FIVE: DOSAGE FORM DESIGN AND MANUFACTURE *Pharmaceutical preformulation *Solutions *Clarification *Suspensions and emulsions *Powders and granules *Granulation *Drying *Tablets and compaction *Modified-release peroral dosage forms *Coating of tablets and multiparticulates *Hard gelatin capsules *Soft gelatin capsules *Pulmonary drug delivery *Nasal drug delivery *Transdermal drug delivery *Wound dressings *Rectal and vaginal drug delivery *Delivery of pharmaceutical proteins *Packs and packaging *Microbial contamination, spoilage and preservation of medicines *Product stability and stability testing *Pharmaceutical plant design *Heat transfer and the properties and use of steam
ER  -