000			01819nam a22003257a 4500
003			KENaKMTC
005			20250423114151.0
008			250423b |||||||| |||| 00| 0 eng d
020			_a9780123820303
020			_a9780123820310
020			_a0123820316
040			_cDLC
050			_aRS403.S552014
100			_aSilverman, Richard B. _eAuthor
245			_aThe organic chemistry of drug design and drug action/ _cRichard B. Silverman and Mark W. Holladay
250			_a3th edition
260			_aSan Diego: _bAcademic Press, _cc2014
300			_a 1 online resource(xviii,517pages): _billustrations; _c29cm
504			_aIncludes Bibliographical references and Index
505			_aCONTENTS 1.Introduction-- 2.Lead discovery and lead modification-- 3.Receptors-- 4.Enzymes-- 5.Enzyme inhibition and inactivation-- 6.Dna-interactive agents-- 7.Drug resistance and drug synergism-- 8.Drug metabolism-- 9.Prodrugs and drug delivery systems.
520			_aThe Organic chemistry of drug design and drug action, Third edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage
650			_aPharmaceutical chemistry
650			_aBioorganic chemistry
650			_aMolecular pharmacology
650			_aDrug Design
650			_aMolecular pharmacology
650			_aPharmacokinetics
700			_a Holladay, Mark W. _eAuthor
942			_2lcc _cBK _xSO
999			_c40300 _d40300