000			03722cam a22003858a 4500
001			17119338
003			KENaKMTC
005			20221207092720.0
008			120110s2012 enka b 001 0 eng
010			_a 2012001019
020			_a9781845939434 (alk. paper)
035			_a(DNLM)101576094
040			_aDNLM/DLC _cKENaKMTC _dDLC
042			_apcc
050	0	0	_aRM267 _b.A554 2012
060	1	0	_aQV 250
082	0	0	_a615.7/92 _223
100			_4GEORGE TEGOS
245	0	0	_aAntimicrobial drug discovery : _bemerging strategies / _ceditors, George Tegos and Eleftherios Mylonakis.
260			_aWallingford, Oxfordshire : _bCABI, _cc2012.
300			_ax, 357 p. : _bill. ; _c25 cm.
490	1		_aAdvances in molecular and cellular microbiology ; _v22
504			_aIncludes bibliographical references and index.
505	0		_aEmerging discovery strategies : an evolving necessity / Anthony R. Ball and George P. Tegos -- The antibiotic crisis / Arnold L. Demain and Jaroslav Spizek -- Structure, genetic regulation, physiology and function of the AcrAB-TolC efflux pump of escerichia coli and salmonella / Leonard Amaral ... [et al.] -- Small molecule efflux pump inhibitors from natural products as a potential source of antimicrobial agents / Sanjay M. Jachak ... [et al.] -- Fungal efflux-mediated resistance : from targets to inhibitors / Brian C. Monk ... [et al.] -- Vacuolar ATPase (V-ATPase) : a model proton pump for antifungal drug discovery -- Karlett J Parra -- Drug tolerance, persister cells and drug discovery / Kim Lewis -- Inhibition of quorum sensing as a novel antimicrobial strategy -- Gilles Brackman, Hans J. Nelis and Tom Coenye -- Filamentous temperature-sensitive mutant Z (FtsZ) protein as an antibacterial target / Jaroslaw M. Boberek ... [et al.] -- Lysostaphin : a silver bullet for staph / John F. Kokai-Kun -- Strategies to identify modified ribosomally synthesized antimicrobials -- Alan J. Marsh ... [et al.] -- QSAR based discovery of antimicrobial peptides active against multidrug resistant bacteria / Christopher D. Fjell ... [et al.] -- Acetyl-CoA carboxylase as a target for antibacterial development / Grover L. Waldrop -- Underexploited targets in LPS biogenenesis for the design of antibacterials / Laura Cipolla ... [et al.] -- Predicting and dissecting biomolecular interactions by information-driven docking / Panagiotis Kastritsis & Alexandre M.J.J Bonvin -- Anti-fungals and anti-fungal drug discovery / Richard Calderone ... [et al.] -- Pathosystematic studies and the rational design of antifungal interventions / Elaine M Bignell and Darius Armstrong-James -- In vivo high-throughput antimicrobial discovery screens utilizing caenorhabditis elegans as an alternative host / Jeffrey J. Coleman and Eleftherios Mylonakis -- Drosophila melanogaster as a versatile model for discovery of drugs effective against human microbe-induced infection and pathology / Yiorgos Apidianakis and Dimitrios P. Kontoyiannis -- Antimicrobial photosensitizers - harnessing the power of light to treat infections / Sulbha K Sharma, Tianhong Dai and Michael R Hamblin -- Nanoparticle platforms for antimicrobial therapy / David Trofa, Joshua D. Nosanchuk -- Antimicrobial activity of carbon nanotubes / Shaobin Liu, Yuan Chen.
650	1	2	_aAnti-Infective Agents _xpharmacology.
650	1	2	_aDrug Design.
650	2	2	_aDisease Models, Animal.
650	2	2	_aHigh-Throughput Screening Assays _xmethods.
650	2	2	_aPhotosensitizing Agents _xpharmacology.
700	1		_aTegos, George.
700	1		_aMylonakis, Eleftherios.
830		0	_aAdvances in molecular and cellular microbiology ; _v22.
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2lcc _cBK _xD.W
999			_c9572 _d9572