02727nam a22004337a 4500 KENaKMTC 20260324073727.0 260324b |||||||| |||| 00| 0 eng d 9781608318049 9781469840543 9781469875330 9781469840536 1608318044 1469840545 1469875330 DLC R853.C55 H85 2013 Hulley Stephen B. Author Designing clinical research/ Stephen B. Hulley (Author), Steven R. Cummings , Warren S. Browner, Deborah Grady , Thomas B. Newman 4th.edition Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, c2013 xiii, 367 pages : illustrations ; 26 cm previous edition published in 2007 by lippincott william &wilkins,a walters kluwer business Includes Bibliographical refrences and Index CONTENTS Sect. I. Basic ingredients: 1.Getting started: the anatomy and physiology of clinical research-- 2.Conceiving the research question and developing the study plan-- 3.Choosing the study subjects: specification, sampling, and recruitment-- 4.Planning the measurements: precision, accuracy, and validity-- 5.Getting ready to estimate sample size: hypotheses and underlying principles-- 6.Estimating sample size and power: applications and examples Sect. II. Study designs: 7.Designing cross-sectional and cohort studies-- 8.Designing case-control studies-- 9.Enhancing casual inference in observational studies-- 10.Designing a randomized blinded trial 11.Alternative clinical trial designs and implementation issues-- 12.Designing studies of medical tests-- 13.Research using existing data-- Sect. III. Implementation: 14.Addressing ethical issues-- 15.Designing questionnaires, interviews, and online surveys-- 16.Data management-- 17.Implementing the study and quality control-- 18.Community and international studies-- 19.Writing a proposal for funding research. "This book provides a practical guide to planning, tabulating, formulating, and implementing clinical research, in an easy-to-use, readable presentation"--Provided by publisher Clinical trials Epidemiologic Methods Epidemiology Research Methodology Medicine Research Methodology Health and Fitness Health and Wellbeing Research Design Cummings Steven R. Author Browner Warren S. Author Grady Deborah Author Newman Thomas B. Author lcc BK SO 0 0 lcc 0 0 001 001 GEN 2026-03-24 0 R853.C55 H85 2013 32997 2026-03-24 04:34:01 2026-03-09 BK 52352 52352