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  <titleInfo>
    <title> Designing clinical research</title>
  </titleInfo>
  <name type="personal">
    <namePart>Hulley Stephen B.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
    <role>
      <roleTerm type="text">Author</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Cummings Steven R.</namePart>
    <role>
      <roleTerm type="text">Author </roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Browner Warren S.</namePart>
    <role>
      <roleTerm type="text">Author</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Grady Deborah</namePart>
    <role>
      <roleTerm type="text">Author</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Newman Thomas B.</namePart>
    <role>
      <roleTerm type="text">Author</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <originInfo>
    <place>
      <placeTerm type="text">Philadelphia</placeTerm>
    </place>
    <publisher>Wolters Kluwer Health/Lippincott Williams &amp; Wilkins</publisher>
    <dateIssued>c2013</dateIssued>
    <edition>4th.edition</edition>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xiii, 367 pages : illustrations ;  26 cm</extent>
  </physicalDescription>
  <abstract>"This book provides a practical guide to planning, tabulating, formulating, and implementing clinical research, in an easy-to-use, readable presentation"--Provided by publisher</abstract>
  <tableOfContents>CONTENTS
Sect. I. Basic ingredients:
1.Getting started: the anatomy and physiology of clinical research--
2.Conceiving the research question and developing the study plan--
3.Choosing the study subjects: specification, sampling, and recruitment--
4.Planning the measurements: precision, accuracy, and validity--
5.Getting ready to estimate sample size: hypotheses and underlying principles--
6.Estimating sample size and power: applications and examples
Sect. II. Study designs:
7.Designing cross-sectional and cohort studies--
8.Designing case-control studies--
9.Enhancing casual inference in observational studies--
10.Designing a randomized blinded trial
11.Alternative clinical trial designs and implementation issues--
12.Designing studies of medical tests--
13.Research using existing data--
Sect. III. Implementation:
14.Addressing ethical issues--
15.Designing questionnaires, interviews, and online surveys--
16.Data management--
17.Implementing the study and quality control--
18.Community and international studies--
19.Writing a proposal for funding research.</tableOfContents>
  <note type="statement of responsibility">Stephen B. Hulley (Author), Steven R. Cummings , Warren S. Browner, Deborah Grady , Thomas B. Newman </note>
  <note>previous edition published in 2007 by lippincott william &amp;wilkins,a walters kluwer business</note>
  <note>Includes Bibliographical refrences and Index</note>
  <subject>
    <topic>Clinical trials</topic>
  </subject>
  <subject>
    <topic>Epidemiologic Methods</topic>
  </subject>
  <subject>
    <topic>Epidemiology Research Methodology</topic>
  </subject>
  <subject>
    <topic>Medicine Research Methodology</topic>
  </subject>
  <subject>
    <topic>Health and Fitness</topic>
  </subject>
  <subject>
    <topic>Health and Wellbeing</topic>
  </subject>
  <subject>
    <topic>Research Design</topic>
  </subject>
  <classification authority="lcc">R853.C55 H85 2013</classification>
  <identifier type="isbn"> 9781608318049</identifier>
  <identifier type="isbn">9781469840543</identifier>
  <identifier type="isbn">9781469875330</identifier>
  <identifier type="isbn">9781469840536</identifier>
  <identifier type="isbn">1608318044</identifier>
  <identifier type="isbn">1469840545</identifier>
  <identifier type="isbn">1469875330</identifier>
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