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  <titleInfo>
    <title>Handbook of neuroemergency clinical trials</title>
  </titleInfo>
  <name type="personal">
    <namePart>Alves, Wayne M.</namePart>
  </name>
  <name type="personal">
    <namePart>Skolnick, Brett Evan.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">ne</placeTerm>
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    <place>
      <placeTerm type="text">London</placeTerm>
    </place>
    <publisher>Elsevier Academic Press</publisher>
    <dateIssued>c2018</dateIssued>
    <dateIssued encoding="marc">2006</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
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    <extent>xix, 386 p. : ill. ; 24 cm.</extent>
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  <tableOfContents>Acute ischemic stroke / Christopher Bladin and Stephen Davis -- Subarachnoid hemorrhage / Nader Pouratian, Aaron S. Dumont, and Neal F. Kassell -- Spontaneous intracerebral hemorrhage / Michael D. Hill -- Traumatic brain injury / Wayne M. Alves and Lawrence F. Marshall -- Acute seizures and status epilepticus / Susan Herman -- Clinical trials in neuro-ophthalmology / Madhura Tamhankar and Laura Balcer -- Brain resuscitation / Edwin Nemoto and Charles C. King -- Clinical trials in brain injury after cardiac arrest / Romergryko G. Geocadin and Daniel F. Hanley --</tableOfContents>
  <tableOfContents>Efficient dose-response finding strategies for acute neuroemergency treatments / Tom Parke ... [et al.] -- Biostatistical issues in neuroemergency clinical trials / Wayne M. Alves -- Data safety and monitoring board: role in acute neurological trials / Brett E. Skolnick -- Role of a project medical officer in acute neuroemergency clinical trials / Joseph A. Kwentus -- Ethical considerations in neuroemergency clinical trials / Wayne M. Alves -- Industry perspective on drug development / Thomas C. Wessel and Christopher Gallen -- Regulatory perspective / Lisa L. Travis.</tableOfContents>
  <note type="statement of responsibility">edited by Wayne M. Alves, Brett E. Skolnick.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Nervous system</topic>
    <topic>Diseases</topic>
    <topic>Handbooks, manuals, etc</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Neuropharmacology</topic>
    <topic>Handbooks, manuals, etc</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Clinical trials</topic>
    <topic>Handbooks, manuals, etc</topic>
  </subject>
  <subject authority="mesh">
    <topic>Central Nervous System Diseases</topic>
    <topic>drug therapy</topic>
  </subject>
  <subject authority="mesh">
    <topic>Neuroprotective Agents</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>Clinical Trials</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Emergency Medicine</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Neuropharmacology</topic>
    <topic>methods</topic>
  </subject>
  <classification authority="lcc">RC346 .H2355 2018</classification>
  <classification authority="ddc" edition="22">616.8/0461</classification>
  <classification authority="nlm">QV 76.5 H2355 2006</classification>
  <identifier type="isbn">0126480826</identifier>
  <identifier type="isbn">9780120885237</identifier>
  <identifier type="lccn">2005027031</identifier>
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    <recordCreationDate encoding="marc">050915</recordCreationDate>
    <recordChangeDate encoding="iso8601">20260519144728.0</recordChangeDate>
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