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  <titleInfo>
    <title>Designing clinical research</title>
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  <name type="personal">
    <namePart>Hulley, Stephen B.</namePart>
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    <place>
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    <publisher>Lippincott Williams &amp; Wilkins</publisher>
    <dateIssued>c2007</dateIssued>
    <dateIssued encoding="marc">2007</dateIssued>
    <edition>3rd ed.</edition>
    <issuance>monographic</issuance>
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    <extent>xv, 367 p. ill. ; 26 cm.</extent>
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  <tableOfContents>Getting started: the anatomy and physiology of clinical research / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Conceiving the research question / Steven R. Cummings, Warren S. Browner, and Stephen B. Hulley -- Choosing the study subjects: specification, sampling, and recruitment / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Planning the measurements: precision and accuracy / Stephen B. Hulley and Steven R. Cummings -- Getting ready to estimate sample size: hypotheses and underlying principles / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Estimating sample size and power: applications and examples / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Designing an observational study: cohort studies / Steven R. Cummings, Thomas B. Newman, and Stephen B. Hulley -- Designing an observational study: cross-sectional and case-control studies / Thomas B. Newman ... [et al.] -- Enhancing causal inference in observational studies / Thomas B. Newman, Warren S. Browner, and Stephen B. Hulley --</tableOfContents>
  <tableOfContents>Designing a randomized blinded trial / Steven R. Cummings, Deborah Grady, and Stephen B. Hulley -- Alternative trial designs and implementation issues / Deborah Grady, Steven R. Cummings, and Stephen B. Hulley -- Designing studies of medical tests / Thomas B. Newman, Warren S. Browner, and Steven R. Cummings -- Research using existing databases: secondary data analysis, ancillary studies, and systematic reviews / Deborah Grady and Norman Hearst -- Addressing ethical issues / Bernard Lo -- Designing questionnaires and interviews / Steven R. Cummings and Stephen B. Hulley -- Data management / Michael A. Kohn -- Implementing the study: pretesting, quality control, and protocol revisions / Stephen B. Hulley and Steven R. Cummings.</tableOfContents>
  <note type="statement of responsibility">Stephen B. Hulley ... [et al.].</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Clinical trials</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Medicine</topic>
    <topic>Research</topic>
    <topic>Methodology</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Epidemiology</topic>
    <topic>Research</topic>
    <topic>Methodology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Epidemiologic Methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Research Design</topic>
  </subject>
  <classification authority="lcc">R853.C55 D47 2007</classification>
  <classification authority="ddc" edition="22">610.72</classification>
  <identifier type="isbn">9780781782104</identifier>
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