03186cam a22003974a 450000100090000000300090000900500170001800800410003501000170007602000180009302000150011103500200012604000230014604200080016905000230017708200150020024500670021525000120028226000630029430000300035750400510038750510680043850507410150665000210224765000370226865000410230565000270234665000210237370000230239485600830241785600910250090600450259194200190263695201160265599900170277114518067KENaKMTC20260701112019.0060824s2007    paua     b    001 0 eng    a  2006028271  a9780781782104  a0781782104  a(DNLM)101285830  aDNLM/DLCcDLCdDLC  apcc00aR853.C55bD47 200700a610.7222200aDesigning clinical research /cStephen B. Hulley ... [et al.].  a3rd ed.  aPhiladelphia, PA :bLippincott Williams & Wilkins,cc2007.  axv, 367 p. ill. ;c26 cm.  aIncludes bibliographical references and index.0 aGetting started: the anatomy and physiology of clinical research / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Conceiving the research question / Steven R. Cummings, Warren S. Browner, and Stephen B. Hulley -- Choosing the study subjects: specification, sampling, and recruitment / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Planning the measurements: precision and accuracy / Stephen B. Hulley and Steven R. Cummings -- Getting ready to estimate sample size: hypotheses and underlying principles / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Estimating sample size and power: applications and examples / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Designing an observational study: cohort studies / Steven R. Cummings, Thomas B. Newman, and Stephen B. Hulley -- Designing an observational study: cross-sectional and case-control studies / Thomas B. Newman ... [et al.] -- Enhancing causal inference in observational studies / Thomas B. Newman, Warren S. Browner, and Stephen B. Hulley --0 aDesigning a randomized blinded trial / Steven R. Cummings, Deborah Grady, and Stephen B. Hulley -- Alternative trial designs and implementation issues / Deborah Grady, Steven R. Cummings, and Stephen B. Hulley -- Designing studies of medical tests / Thomas B. Newman, Warren S. Browner, and Steven R. Cummings -- Research using existing databases: secondary data analysis, ancillary studies, and systematic reviews / Deborah Grady and Norman Hearst -- Addressing ethical issues / Bernard Lo -- Designing questionnaires and interviews / Steven R. Cummings and Stephen B. Hulley -- Data management / Michael A. Kohn -- Implementing the study: pretesting, quality control, and protocol revisions / Stephen B. Hulley and Steven R. Cummings. 0aClinical trials. 0aMedicinexResearchxMethodology. 0aEpidemiologyxResearchxMethodology.12aEpidemiologic Methods.22aResearch Design.1 aHulley, Stephen B.413Table of contents onlyuhttp://www.loc.gov/catdir/toc/ecip0619/2006028271.html423Publisher descriptionuhttp://www.loc.gov/catdir/enhancements/fy0712/2006028271-d.html  a7bcbccorignewd1eecipf20gy-gencatlg  2lcccBKxG.O.O  00102lcc4070a031b031cGENd2026-07-01l0oR853.C55 D47 2007pBND/0799r2026-07-01 11:22:00w2026-07-01yBK  c61888d61888