000 02943cam a2200373 i 4500
001 19018172
003 KENaKMTC
005 20230130092627.0
008 160316s2017 enka b 001 0 eng c
010 _a 2016936209
016 7 _a101703465
_2DNLM
020 _a9780128037836
_q(hardcover)
020 _a0128037830
_q(hardcover)
035 _a(OCoLC)ocn957503524
040 _aNLM
_beng
_cDLC
_erda
_dBDX
_dYDX
_dWSU
_dBTCTA
_dNLM
_dOCLCO
_dDLC
042 _apcc
050 0 0 _aRC382.P24 2017
060 0 0 _a2017 C-367
060 1 0 _aWL 359
082 0 0 _a616.8/33
_223
130 0 _aParkinson's disease (Verstreken)
245 1 0 _aParkinson's disease : molecular mechanisms underlying pathology /
_cBy Patrik Verstreken,
260 _aLondon :
_bElservier,
_cc2017.
300 _axii, 318 pages. :
_billustrations. ;
_c24 cm
504 _aIncludes bibliographical references and index.
505 0 _aThe neurogenetics of Parkinson's Disease and putative links to other neurodegenerative disorders / C.M. Lill, C. Klein -- Electron transport train / L. Aerts, V.A. Morais -- Mitochondrial fission and fusion / V.L. Hewitt, A.J. Whitworth -- Axonal mitochondrial transport / E. Shlevkov, T.L. Schwarz -- Mitophagy / L. King, H. Plun-Favreau -- Autophagy / P.A. Lewis, M. Perez-Carrion, G. Piccoli -- Endocytosis and synaptic function / S.F. Soukup, P. Verstreken, S. Vilain -- Neuroinflammation as a potential mechanism underlying Parkinsons Disease / C. Cebrián, D. Sulzer -- Protien translation in Parkinson's Disease / J.W. Kim, L. Abalde-Atristain, H. Jia, I. Martin, T.M. Dawson, V.L. Dawson.
520 _aParkinson's Disease: Molecular Mechanisms Underlying Pathology explores the molecular pathways at the basis of the cellular defects connected to Parkinson's disease, the second most common neurodegenerative disease, and the most common movement disorder. This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. This focus on mechanisms rather than individual genes allows the contributors to elaborate on overlapping and joint functions of different causative genes. Readers will find descriptions of model systems that present parallels (and differences) between discoveries in different species, demonstrating the importance of multidisciplinary research that spans a broad array of technologies and model organisms. Written from both a cross-methodology and cross-species perspective, the book provides readers with the current state of knowledge on the molecular biology of Parkinson's
650 0 _aParkinson's disease
_xMolecular aspects.
650 1 2 _aParkinson Disease
_xphysiopathology.
700 1 _aVerstreken, Patrik,
906 _a7
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999 _c12339
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