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050 0 0 _aRS403.F69 2008
082 0 0 _a616.07/56
_222
245 0 0 _aFoye's principles of medicinal chemistry /
_cedited by Thomas L. Lemke, David A. Williams ; assistant editors, Victoria F. Roche, S. William Zito ... [et al.].
246 3 0 _aPrinciples of medicinal chemistry
250 _a6th ed.
260 _aNew Delhi :
_bWolters Kluwer/Lippincott Williams & Wilkins,
_cc2008.
300 _axiv, 1377 p., 8 p. of plates ;
_bill. (some col.)
_c29 cm.
504 _aIncludes bibliographical references and index.
505 _aHistorical perspective of medicinal chemistry / John L. Neumeyer -- pt. I: Principles of drug discovery -- Chapter 1: Drug discovery from natural products / A. Douglas Kinghorn -- Chapter 2: Drug design and relationship of functional groups to pharmacologic activity / James J. Knittel and Robin M. Zavod -- Chapter 3: Molecular modeling and in Silico drug design / Xiang-Qun (Sean) Xie -- Chapter 4: Receptors and drug action / Timothy A. Maher and David A. Johnson -- Chapter 5: Drug discovery through enzyme inhibition / Stephen Kerr -- Chapter 6: Pharmaceutical biotechnology-from nucleic acids to personalized medicine / Ronald E. Reid and Robert D. Sindelar -- Chapter 7: Peptide and protein drugs / Michael Mokotoff -- Chapter 8: Antisense therapeutic agents / Marilyn Speedie -- Chapter 9: Physicochemical and biopharmaceutical properties of drug substances and pharmacokinetics / Sunil S. Jambhekar -- Chapter 10: Drug metabolism / David A. Williams -- Chapter 11: U.S. drug regulation: an overview / Douglas -- Part II: Drug receptors affecting neurotransmission and enzymes as catalytic receptors : overview of Drug Receptors: A Perspective / David J. Triggle -- Chapter 12: Drugs affecting cholinergic neurotransmission / E. Kim Fifer -- Chapter 13: Adrenergic receptors and drugs affecting adrenergic neurotransmission / Robert K. Griffith -- Chapter 14: Serotonin receptors and drugs affecting serotonergic neurotransmission / Richard A. Glennon and Malgorzata Dukat-Glennon -- Chapter 15: Amino acid neurotransmitters in the central nervous system / Timothy J. Maher -- Chapter 16: Inhibitors of nerve conduction: local anesthetics / Matthias C. Lu -- Chapter 17: Phosphodiesterase inhibitors / Kevin Dalby -- Part III: Pharmacodynamic Agents -- Section 1: Drugs affecting central nervous system -- Chapter 18: General anesthetics / Timothy J. Maher -- Chapter 19: Sedative-hypnotics / William Soine -- Chapter 20: Antiseizure agents / Barbara Leduc -- Chapter 21: Antidepressants / David A. Williams -- Chapter 22: Psychotherapeutic drugs: antipsychotic and anxiolytic agents / Raymond G. Booth -- Chapter 23: Hallucinogens, stimulants and related drugs of abuse / Richard A. Glennon -- Chapter 24: Opioid analgesics / David S. Fries -- Chapter 25: Drugs used to treat neuromuscular disorders: antiparkinsonian and spasmolytic agents / Raymond G. Booth. Section 2: Drugs affecting the cardiovascular system -- Chapter 26: Cardiac agents: Cardiac glycosides, antianginal, and antiarrhythmic drugs / Ahmed S. Mehanna -- Chapter 27: Diuretics / Gary O. Rankin -- Chapter 28: Angiotensin converting enzyme inhibitors, antagonists and calcium blockers / Marc Harrold -- Chapter 29: Central and peripheral sympatholytics and vasodilators / David A. Williams -- Chapter 30: Antihyperlipoproteinemics and inhibitors of cholesterol biosynthesis / Marc Harrold -- Chapter 31: Antithrombotics, thrombolytics, coagulants, and plasma extenders / Matthias C. Lu and Thomas L. Lemke -- Section 3: Drugs affecting the hormonal systems -- Chapter 32: Insulin and drugs used for the treatment of diabetes / Robin M. Zavod, John L. Krstenansky, and Bruce L. Currie -- Chapter 33: Adrenocorticoids / Duane D. Miller, Robert W. Brueggemeier and James T. Dalton -- Chapter 34: Thyroid function and thyroid drugs / Ali R. Banijamali -- Chapter 35: Calcium homeostasis / Robin M. Zavod -- Section 4: Drugs affecting the immune systems -- Chapter 36: Nonsteroidal anti-inflammatory drugs / Wendel L. Nelson -- Chapter 37: Antihistamines and related antiallergic and antiulcer agents -- Section 5: Chemotherapeutic agents -- Chapter 38: Antibiotics and antimicrobial agents / Lester A. Mitscher, Thomas L. Lemke, and Elmer J. Gentry -- Chapter 39: Antiparasitic agents: Thomas L. Lemke -- Chapter 40: Antifungal agents / Robert K. Griffith -- Chapter 41: Antimycobacterial agents /Thomas L. Lemke -- Chapter 42: Cancer and chemotherapy / Victoria F. Roche -- Chapter 43: Antiviral agents and protease inhibitors / Patrick M. Woster -- Part IV: Disease state management -- Chapter 44: Asthma and chronic obstructive pulmonary disease S. William Zito -- Chapter 45: Men' Health / Duane D. Miller, Robert W. Brueggermeier, and James T. Dalton -- Chapter 46: Women's Health / Robin M. Zavod.
520 _aThis comprehensive text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist. A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men's and women's health problems. Read more...
650 0 _aPharmaceutical chemistry.
650 1 2 _aChemistry, Pharmaceutical.
700 1 _aFoye, William O.
700 1 _aLemke, Thomas L.
700 1 _aWilliams, David A.,
_d1938-
856 4 2 _3Publisher description
_uhttp://www.loc.gov/catdir/enhancements/fy0912/2007026228-d.html
856 4 1 _3Table of contents only
_uhttp://www.loc.gov/catdir/enhancements/fy0912/2007026228-t.html
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