000			02727nam a22004337a 4500
003			KENaKMTC
005			20260324073727.0
008			260324b |||||||| |||| 00| 0 eng d
020			_a 9781608318049
020			_a9781469840543
020			_a9781469875330
020			_a9781469840536
020			_a1608318044
020			_a1469840545
020			_a1469875330
040			_cDLC
050			_aR853.C55 H85 2013
100			_aHulley Stephen B. _eAuthor
245			_a Designing clinical research/ _cStephen B. Hulley (Author), Steven R. Cummings , Warren S. Browner, Deborah Grady , Thomas B. Newman
250			_a4th.edition
260			_a Philadelphia: _bWolters Kluwer Health/Lippincott Williams & Wilkins, _cc2013
300			_axiii, 367 pages : _billustrations ; _c26 cm
500			_aprevious edition published in 2007 by lippincott william &wilkins,a walters kluwer business
504			_aIncludes Bibliographical refrences and Index
505			_aCONTENTS Sect. I. Basic ingredients: 1.Getting started: the anatomy and physiology of clinical research-- 2.Conceiving the research question and developing the study plan-- 3.Choosing the study subjects: specification, sampling, and recruitment-- 4.Planning the measurements: precision, accuracy, and validity-- 5.Getting ready to estimate sample size: hypotheses and underlying principles-- 6.Estimating sample size and power: applications and examples Sect. II. Study designs: 7.Designing cross-sectional and cohort studies-- 8.Designing case-control studies-- 9.Enhancing casual inference in observational studies-- 10.Designing a randomized blinded trial 11.Alternative clinical trial designs and implementation issues-- 12.Designing studies of medical tests-- 13.Research using existing data-- Sect. III. Implementation: 14.Addressing ethical issues-- 15.Designing questionnaires, interviews, and online surveys-- 16.Data management-- 17.Implementing the study and quality control-- 18.Community and international studies-- 19.Writing a proposal for funding research.
520			_a"This book provides a practical guide to planning, tabulating, formulating, and implementing clinical research, in an easy-to-use, readable presentation"--Provided by publisher
650			_aClinical trials
650			_aEpidemiologic Methods
650			_aEpidemiology Research Methodology
650			_aMedicine Research Methodology
650			_aHealth and Fitness
650			_aHealth and Wellbeing
650			_aResearch Design
700			_aCummings Steven R. _eAuthor
700			_aBrowner Warren S. _eAuthor
700			_aGrady Deborah _eAuthor
700			_aNewman Thomas B. _eAuthor
942			_2lcc _cBK _xSO
999			_c52352 _d52352